Principal Scientist, Cheminformatics/Data sciences

  • Morphic Therapeutic
  • Waltham, MA, USA
  • Mar 26, 2020
Full time Biotech Science

Job Description

About Morphic Therapeutic Morphic Therapeutic is a biotechnology company developing oral integrin therapies. Drawing on integrin biology breakthroughs from the lab of noted entrepreneur and scientific founder Dr. Timothy A. Springer, Morphic has developed an exclusive MInT platform that facilitates the rapid discovery of clinical candidates. Morphic was created in 2015 and raised $51.5M in 2016 from top tier investors. In 2018, Morphic Therapeutic completed an $80 million Series B financing round and formed a collaboration with Abbvie Inc. focused on the exploration of TGF-β biology in fibrotic diseases. In 2019 Morphic formed a collaboration with Janssen Biotech, a Johnson and Johnson company to explore the potential of integrin inhibitors and activators in multiple diseases. On Jun. 26, 2019 Morphic announced the pricing of its upsized initial public offering of 6,000,000 shares of its common stock at a price to the public of $15.00 per share. The shares are trading on The Nasdaq Global Market under the symbol "MORF." Currently, we are advancing both partnered and fully-owned oral integrin therapeutic candidates into the clinic with an anticipated first IND filing as early as the end of the year. Integrin dysregulation is involved in multiple diseases that span, including inflammation, fibrosis, vascular diseases, and cancer. Our immediate focus is on the areas where the clinical activity of antibody inhibitors of integrins is precedented, thus enabling a rapid path to clinical proof-of-concept. The Morphic Therapeutic office is located in the AstraZeneca BioHub in Waltham, MA. We are seeking a highly talented and motivated individual to join our culture of teamwork, craftsmanship, tenacity, compassion, and integrity. Job Description:
Morphic Therapeutic is seeking a highly motivated, experienced, and accomplished cheminformatics/data scientist. This person will work closely with Morphic and partnered scientists to deliver modern cheminformatic capabilities to project teams, aiding in the advancement of multiple early - late stage projects. At the same time, the successful candidate will contribute to the design and execution of the overall data strategy for the company.
Responsibilities Design, implement and maintain robust tools, methods, visualizations, etc. to enhance the digestion of multi-parameter structure activity relationships. Build applicable predictive models to allow more informed decision making. Influence and execute an overall data management strategy focusing on efficiency and ease of data flow. Work closely with internal medicinal chemists, biologists, DMPK and other scientists to assess current informatics needs and implement workable solutions Build strong relationships with internal and external scientists and work in a highly collaborative manner Advance projects through use of these tools directly towards clinical candidates to impact patients Category: Science , Keywords: Senior Scientist